Objective: Review contemporary theory, research, and methods relevant to the scientific study of infant development. Topics include physiological, cortical, motor, perceptual, cognitive, emotional, and social development in infancy. Human and other animal models will be considered. The course focuses on both normative and atypical (e.g., autism) development because an understanding of one enriches an understanding of the other.

Required Readings: The class is a seminar with students reading and discussing key journal articles and reviews, which are linked to this syllabus. One reading will be assigned for each class. Reading assignments marked "Extra" are suggested but not required.

Facilitating Discussions: Students will present readings and facilitate class discussion several times during the semester. Your presentations should cover the results, methods if relevant, integrative themes across the readings, and ideas regarding potential future directions/applications of the findings. Give us the big picture but know the details! To do so, please familiarize yourself with the online slides you may use to present your article. As needed, please edit the slides and create new slides. If you create a new slide, please put your last name in the footer section of the slide. I favor the use of figures in slides. Slides are due by email 12 hours before class. Presentation/discussions are 25% of your grade and will be based on the clarity and thoughtfulness of your presentation and the ensuing discussion.

Participation: Attendance is mandatory and 10% of your grade will be based on your engagement and participation in classroom discussions. This may include written responses to in-class queries.

Final project. A written and verbally presented project on typical or atypical infant development that interests you and will foster your productivity (65% of grade). The final project is designed by the student and mentored by the professor to foster interdisciplinary student productivity. Examples:

1) A publication-quality research project such as a thesis or paper.

2) A NSF or NIH research or training grant proposal (all sections).

3) A publication quality literature reviews in summary-article/chapter format (i.e., organized by theme, not by reading).

Due dates:

8/30. Title and type of project (grant, paper, etc.).

9/13. One paragraph single-spaced summary.

9/27. One page single-spaced abstract of intended final project.

10/11. Two page single-spaced abstract of your final project.

11/1. First draft of final paper.

11/15. Draft PowerPoint and oral presentation.

12/6. PowerPoint and oral presentation.

12/14. Final paper due.

Be prepared to discuss your final project progress in class on these dates. Consult with your PI on your project and cc your PI when you submit each of these assignments. You can change your final project topic at any point but you will not benefit from comments on the previous topic.

Honor code: Final project assignments will be submitted through BlackBoard SafeAssign. They are governed by the Honor code: “On my honor, I have neither given nor received any aid on this exam/paper, etc.” Review the graduate honor code here.

Schedule of Classes and Assigned Readings

Tuesday, August 23.Introduction to infancy and to the class.

Thursday, August 25. Developmental Design, Measurement, & Analysis (i2.design.ppt) Katherine1

Adolph, K. E., S. R. Robinson, et al. (2008). "What is the shape of developmental change?" Psychological Review 115(3): 527-543.

Extra:

Bornstein & Lamb: Chapter 3. Hartmann, D. P. & Pelzel, K. E., & Abbott, C. B. (2011). Design, Measurement, and Analysis in Developmental Research.

Spencer, J. P., Perone, S., & Buss, A. T. (2011). Twenty years and going strong: A dynamic systems revolution in motor and cognitive development. Child Development Perspectives, 5, 260-266.

Tuesday, August 30. Physical growth and motor development.

Kretch, K. S., & Adolph, K. E. (2016). The organization of exploratory behaviors in infant locomotor planning. Dev Sci. doi: 10.1111/desc.12421 Emily1

Thursday, September 1. Culture in Development

Wörmann, V., Holodynski, M., Kärtner, J., & Keller, H. (2014). The emergence of social smiling: The interplay of maternal and infant imitation during the first three months in cross-cultural comparison. Journal of Cross-Cultural Psychology, 45(3), 339-361. doi: 10.1177/0022022113509134 Chelsea1

Extra:

Wang L. & Mesman J. (2015), Child development in the face of rural-to-urban migration in China: A meta-analytic review, Perspectives on Psychological Science 10(6): 813-831.

Bornstein & Lamb: Chapter 2. Cole, M., & Packer, M. (2011). Culture in development.

Babies—the movie https://vimeo.com/30328533

Tuesday, September 6. Genetics.

Kozol, R. A., Abrams, A. J., James, D. M., Buglo, E., Yan, Q., & Dallman, J. E. (2016). Function Over Form: Modeling Groups of Inherited Neurological Conditions in Zebrafish. Frontiers in Molecular Neuroscience, 9(55). doi: 10.3389/fnmol.2016.00055. David1

Extra:

Two knockdown models of the autism genes SYNGAP1 and SHANK3 in zebrafish produce similar behavioral phenotypes associated with embryonic disruptions of brain morphogenesis. Kozol RA, Cukier HN, Zou B, Mayo V, De Rubeis S, Cai G, Griswold AJ, Whitehead PL, Haines JL, Gilbert JR, Cuccaro ML, Martin ER, Baker JD, Buxbaum JD, Pericak-Vance MA, Dallman JE. Hum Mol Genet. 2015 Jul 15;24(14):4006-23. doi: 10.1093/hmg/ddv138.

Thursday, September 8. Epigenetics

Szyf, M., & Bick, J. (2012). DNA Methylation: A Mechanism for Embedding Early Life Experiences in the Genome. Child Development, no-no. doi: 10.1111/j.1467-8624.2012.01793.x Katherine2

Extra:

Lister, R., Mukamel, E. A., Nery, J. R., Urich, M., Puddifoot, C. A., Johnson, N. D., Lucero, J., Huang, Y., Dwork, A. J., Schultz, M. D., Yu, M., Tonti-Filippini, J., Heyn, H., Hu, S., Wu, J. C., Rao, A., Esteller, M., He, C., Haghighi, F. G., Sejnowski, T. J., Behrens, M. M., & Ecker, J. R. (2013). Global epigenomic reconfiguration during mammalian brain development. Science, 341(6146), 1237905. doi: 10.1126/science.1237905.

Naumova, O. Y., Hein, S., Suderman, M., Barbot, B., Lee, M., Raefski, A., Dobrynin, P. V., Brown, P. J., Szyf, M., Luthar, S. S., & Grigorenko, E. L. (2016). Epigenetic Patterns Modulate the Connection Between Developmental Dynamics of Parenting and Offspring Psychosocial Adjustment. Child Dev, 87(1), 98-110. doi: 10.1111/cdev.12485

Tuesday, September 13. Brain, body, and experience (ppt)

Bernier, A., Calkins, S. D., & Bell, M. A. (2016). Longitudinal Associations Between the Quality of Mother–Infant Interactions and Brain Development Across Infancy. Child Development, 87(4), 1159-1174. doi: 10.1111/cdev.12518 Emily2

Extra:

Fox, S. E., Levitt, P., & Nelson, C. A., 3rd. (2010). How the timing and quality of early experiences influence the development of brain architecture. Child Dev, 81(1), 28-40.

Uddin, L. Q., Supekar, K., & Menon, V. (2013). Reconceptualizing functional brain connectivity in autism from a developmental perspective. Frontiers in Human Neuroscience, 7. doi: 10.3389/fnhum.2013.00458

Chen, E., Cohen, S., & Miller, G. E. (2010). How low socioeconomic status affects 2-year hormonal trajectories in children. Psychological Science, 21, 31-37.

Thursday, September 15.

Perceptual Development (ppt)

Jakobsen, K., Umstead, L., & Simpson, E. (2015). Efficient human face detection in infancy. Developmental Psychobiology, 58(1), 129-136. Chelsea2

Simpson, E. A., Jakobsen, K. V., Damon, F., Suomi, S. J., Ferrari, P. F., & Paukner, A. (2016). Face Detection and the Development of Own-Species Bias in Infant Macaques. Child Development, n/a-n/a. doi: 10.1111/cdev.12565

Extra:

Simpson, E. A., Suomi, S. J., & Paukner, A. (2016). Evolutionary Relevance and Experience Contribute to Face Discrimination in Infant Macaques (Macaca mulatta). Journal of Cognition and Development, 17(2), 285-299. doi: 10.1080/15248372.2015.1048863

Bornstein & Lamb: Chapter 6. Bornstein, M. H., Arterberry, M. E., & Mash, C. (2011). Perceptual development.

~~Tuesday, September 20. Perceptual Development~~ (ppt10) No class

Vogel, M., Monesson, A., & Scott, L. S. (2012). Building biases in infancy: The influence of race on face and voice emotion matching. Developmental Science, 15, 359-372.

Papageorgiou, K. A., Smith, T. J., Wu, R., Johnson, M. H., Kirkham, N. Z., & Ronald, A. (2014). Individual Differences in Infant Fixation Duration Relate to Attention and Behavioral Control in Childhood. Psychological Science. doi: 10.1177/0956797614531295

Jones, W., & Klin, A. (2013). Attention to eyes is present but in decline in 2-6-month-old infants later diagnosed with autism. Nature, 504(7480), 427-431. doi: 10.1038/nature12715 David2

Extra:

Maurer, D., Mondloch, C. J., & Lewis, T. L. (2007). Sleeper effects. Developmental Science, 10, 40-47.

Maurer, D., & Werker, J. Perceptual narrowing during infancy: A comparison of language and faces. Developmental Psychobiology, 2014, 56, 154-178.

Peterson, D. (2016). The Baby Factory: Difficult Research Objects, Disciplinary Standards, and the Production of Statistical Significance. Socius: Sociological Research for a Dynamic World, 2. doi: 10.1177/2378023115625071

Thursday, September 22. Cognitive Development (ppt11)

Yu, C., & Smith, L. B. (2016). The Social Origins of Sustained Attention in One-Year-Old Human Infants. Curr Biol, 26(9), 1235-1240. doi: 10.1016/j.cub.2016.03.026 Katherine3

Lauer, J. E., & Lourenco, S. F. (2016). Spatial Processing in Infancy Predicts Both Spatial and Mathematical Aptitude in Childhood. Psychological Science. doi: 10.1177/0956797616655977

Simpson, E. A., Murray, L., Paukner, A., & Ferrari, P. F. (2014). The mirror neuron system as revealed through neonatal imitation: Presence from birth, predictive power, and evidence of plasticity. Philosophical Transactions of the Royal Society B, 369(1644), 1-12.

Extra:

Lewkowicz, D. J. (2013). Development of ordinal sequence perception in infancy. Developmental Science, n/a-n/a. doi: 10.1111/desc.12029

Nisbett, R.E., Aronson. J., Blair, C., Dickens, W., Flynn, J., Halpern, D., & Turkheimer, E. (2012). Intelligence: New findings and theoretical developments. American Psychologist, 67, 130-159

Tuesday, September 27. Cognitive Development (ppt).

Tucker-Drob, E. M., & Bates, T. C. (2015). Large Cross-National Differences in Gene × Socioeconomic Status Interaction on Intelligence. Psychological Science. doi: 10.1177/0956797615612727 Chelsea3

Cantrell, L., Boyer, T., Cordes, S. & Smith, L. B. (2015) Signal clarity: an account of the variability in infant quantity discrimination tasks. Developmental Science, 18(6): 877-893.

Extra:

Byrge, L., Sporns, O. & Smith, L. B. (in press) Developmental process emerges from extended brain-body-behavior networks. Trends in Cognitive Sciences. doi:10.1016/j.tics.2014.04.010 short

Tucker-Drob, E. M., Rhemtulla, M., Harden, K. P., Turkheimer, E., & Fask, D. (2010). Emergence of a Gene Ã— Socioeconomic Status Interaction on Infant Mental Ability Between 10 Months and 2 Years. Psychological Science, 22(1), 125-133.

Thursday, September 29. Language Development (ppt)

Warlaumont, A. S., Richards., J. A., Gilkerson, J., & Oller, D. K. (2014). A social feedback loop for speech development and its reduction in autism. Psychological Science, 25(7), 1314–1324. doi: 10.1177/0956797614531023 [supplemental materials] Emily3

Oller DK, Niyogi P, Gray S, Richards JA, Gilkerson J, Xu D, Yapanel U, Warren SF: Automated vocal analysis of naturalistic recordings from children with autism, language delay, and typical development. Proceedings of the National Academy of Sciences 2010, 107:13354-13359.

Perry, L.K., Perlman, M., & Lupyan, G. (2015) Iconicity in English and Spanish and its relation to lexical category and age of acquisition. PLoS ONE.

Perry, L.K., Samuelson, L.K., & Burdinie, J.B. (2014) Highchair philosophers: the role of context-dependent exploration on young children's naming biases. Developmental Science, 17(5), 757-765. David3

Extra:

Bornstein & Lamb: Chapter 8. MacWhinney, B. (2011). Language Development.

Tuesday, October 4. Language Development (ppt14)

Hoff, E. (2013). Interpreting the early language trajectories of children from low SES and language minority homes: Implications for closing achievement gaps. Developmental Psychology, 49, 4-14. DOI: 10.1037/a0027238

Hoff, E. (2003). The Specificity of Environmental Influence: Socioeconomic Status Affects Early Vocabulary Development Via Maternal Speech. Child Development, 74(5), 1368–1378.

Tamis-LeMonda, C. S., Song, L., Kuchirko, Y., & Luo, R. (2014). Children’s

Language Growth in Spanish and English across Early Development and Associations with School Readiness. Developmental Neuropsychology, 39 (2), 69-87.

Goldstein, M. H., Schwade, J. A., & Bornstein, M. H. (2009). The value of vocalizing: Five-month-old infants associate their own noncry vocalizations with responses from adults. Child Development, 80 (3), 636 – 644.

Extra:

Goldstein, M. H., & Schwade, J. A. (2008). Social Feedback to Infants' Babbling Facilitates Rapid Phonological Learning. Psychological Science, 19(5), 515-523. doi: 10.1111/j.1467-9280.2008.02117.x

Cruz, I., Quittner, A. L., Marker, C., DesJardin, J. L., & the, C. I. T. (2013). Identification of Effective Strategies to Promote Language in Deaf Children with Cochlear Implants. Child Development, 84(2), 543-559. doi: 10.1111/j.1467-8624.2012.01863.x

T Tardif, P Fletcher, W Liang, Z Zhang, N Kaciroti, VA Marchman (2008). Baby's first 10 words. Developmental Psychology 44 (4), 929

Werker, J. F., Yeung, H. H., & Yoshida, K. A. (2012). How Do Infants Become Experts at Native-Speech Perception? Current Directions in Psychological Science, 21(4), 221-226.doi: 10.1177/0963721412449459

Thursday, October 6. Emotion (ppt)

Mattson, W. I., Cohn, J. F., Mahoor, M. H., Gangi, D. N., & Messinger, D. S. (2013). Darwin’s Duchenne: Eye constriction during infant joy and distress. PLOS ONE, 8(11). doi: 10.1371/journal.pone.0080161 Katherine4

Extra:

Cole, P. M., & Moore, G. A. (2015). About face! Infant facial expression of emotion. 7, 116-120. doi: 10.1177/1754073914554786

Camras, L. A. (2011). Differentiation, Dynamical Integration and Functional Emotional Development. Emotion Review, 3(2), 138-146. doi: 10.1177/1754073910387944

Tuesday, October 11. Temperament (ppt)

Penela, E. C., Walker, O. L., Degnan, K. A., Fox, N. A., & Henderson, H. A. (2015). Early behavioral inhibition and emotion regulation: Pathways toward social competence in middle childhood. Child Development, 86(4), 1227-1240.doi: 10.1111/cdev.12384 Chelsea4

Fraley, R. C., Griffin, B. N., Belsky, J., & Roisman, G. I. (2013). Developmental antecedents of political ideology: A longitudinal investigation from birth to age 18. Psychological Science, 23, 1425-1431

Extra:

Degnan, K. A., Hane, A. A., Henderson, H. A., Moas, O. L., Reeb-Sutherland, B. C., & Fox, N. A. (2010) Longitudinal stability of temperamental exuberance and social-emotional outcomes in early childhood. Developmental Psychology.

Thursday, October 13. Socialization Experiences I. Parent-child relationships (ppt)

Mesman, J., M. H. van Ijzendoorn, et al. (2009). "The many faces of the Still-Face Paradigm: A review and meta-analysis." Developmental Review 29(2): 120-162. Emily4

Hane, A. A., & Fox, N. A. (2006). Ordinary variations in maternal caregiving of human infants influence stress reactivity. Psychological Science, 17, 550-556.

Sheridan, M. A., N. A. Fox, et al. (2012). "Variation in neural development as a result of exposure to institutionalization early in childhood." Proceedings of the National Academy of Sciences.

Ruvolo, P., Messinger, D., & Movellan, J. (2015). Infants time their smiles to make their moms smile. PLOS ONE, 10(9), e0136492. doi: 10.1371/journal.pone.0136492.

Drury, S.S., Theall, K.P., Gleason, M.M., Smyke, A.T., Devivo, I., Wong, J.Y.Y., Fox, N.A., Zeanah, C.H., & Nelson, C.A. (2012). Telomere length and early severe social deprivation: Linking early adversity and cellular aging. Molecular Psychiatry, 17(7), 719-727. PMID: 21577215.

Extra:

Reeb-Sutherland, B.C., Levitt, P., & Fox, N.A. (2012). The predictive nature of individual differences in early associative learning and emerging social behavior. PLoS ONE; 7: e30511. PDF

van IJzendoorn, M. H., Belsky, J., & Bakermans-Kranenburg, M. J. (2012). Serotonin transporter genotype 5HTTLPR as a marker of differential susceptibility? A meta-analysis of child and adolescent gene-by-environment studies. Transl Psychiatry, 2, e147. doi: 10.1038/tp.2012.73

Belsky, J. & Pluess, M. (2009). Beyond diathesis-stress: Differential susceptibility to environmental influences. Psychological Bulletin, 135, 885-908.

Bornstein & Lamb: Chapter 10. Lamb, M. E., & Lewis, C. (2011). The role of parent-child relationships in child development.

Tuesday, October 18. Parenthood (ppt)

Weisman, O., et al. (2012). "Oxytocin administration to parent enhances infant physiological and behavioral readiness for social engagement." Biological Psychiatry 72(12): 982 989. David4

Extra.

Lee, D., Brooks-Gunn, J., McLanahan, S. S., Notterman, D., & Garfinkel, I. (2013). The Great Recession, genetic sensitivity, and maternal harsh parenting. Proceedings of the National Academy of Sciences, 110(34), 13780-13784. doi: 10.1073/pnas.1312398110

Rilling, J. K., & Young, L. J. (2014). The biology of mammalian parenting and its effect on offspring social development. Science, 345(6198), 771-776. doi: 10.1126/science.1252723

Abraham, E., Hendler, T., Shapira-Lichter, I., Kanat-Maymon, Y., Zagoory-Sharon, O., Feldman, R. (2014). Father’s brain is sensitive to childcare experiences. PNAS.

Thursday, October 20. No Class—Fall Break!

Tuesday, October 25. Socialization Experiences I. Parent-child relationships. (ppt18)

Raby, K. L., Cicchetti, D., Carlson, E. A., Cutuli, J. J., Englund, M. M., & Egeland, B. (2012). Genetic and Caregiving-Based Contributions to Infant Attachment. Psychological Science, 23(9), 1016-1023. doi: 10.1177/0956797612438265 Emily5

Luijk, M. P. C. M., Roisman, G. I., Haltigan, J. D., Tiemeier, H., Booth‐LaForce, C., van Ijzendoorn, M. H., Belsky, J., Uitterlinden, A. G., Jaddoe, V. W. V., Hofman, A., Verhulst, F. C., Tharner, A., & Bakermans‐Kranenburg, M. J. (2011). Dopaminergic, serotonergic, and oxytonergic candidate genes associated with infant attachment security and disorganization? In search of main and interaction effects. Journal of Child Psychology and Psychiatry, 52(12), 1295-1307. doi: 10.1111/j.1469-7610.2011.02440.x

Extra:

Raby, K. L., Roisman, G. I., Fraley, R. C., & Simpson, J. A. (2014). The Enduring Predictive Significance of Early Maternal Sensitivity: Social and Academic Competence through Age 32 Years. Child Development, n/a-n/a. doi: 10.1111/cdev.12325

Beijersbergen, M. D., Juffer, F., Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2012). Remaining or becoming secure: Parental sensitive support predicts attachment continuity from infancy to adolescence in a longitudinal adoption study. Developmental Psychology, 48(5), 1277-1282. doi: 10.1037/a0027442

Sung, S., Simpson, J. A., Griskevicius, V., Kuo, S. I.-C., Schlomer, G. L., & Belsky, J. (2016). Secure Infant-Mother Attachment Buffers the Effect of Early-Life Stress on Age of Menarche. Psychological Science. doi: 10.1177/0956797616631958

Extra:

Thursday, October 27. No class.

Tuesday, November 1.

Socialization Experiences I. Parent-child relationships (ppt)

Kochanska, G., & Kim, S. (2013). Early attachment organization with both parents and future behavior problems: From infancy to middle childhood. Child Development, 84(1), 283-296. doi: 10.1111/j.1467-8624.2012.01852.x Katherine5

MacKenzie, M. J., Nicklas, E., Waldfogel, J., & Brooks-Gunn, J. (2013). Spanking and Child Development Across the First Decade of Life. Pediatrics. doi: 10.1542/peds.2013-1227

Elizabeth T. Gershoff, Andrew Grogan-Kaylor. Spanking and Child Outcomes: Old Controversies and New Meta-Analyses. Journal of Family Psychology, 2016; DOI: 10.1037/fam0000191

Extra:

Huston, A. C., & Aronson, S. R. (2005). Mothers’ time with infant and time in employment as predictors of mother-child relationships and children’s early development. Child Development, 76, 467.

Beijersbergen, M. D., Juffer, F., Bakermans-Kranenburg, M. J., & van Ijzendoorn, M. H. (2012). Remaining or becoming secure: Parental sensitive support predicts attachment continuity from infancy to adolescence in a longitudinal adoption study. Developmental Psychology, 48(5), 1277-1282. doi: 10.1037/a0027442

Thursday, November 3.

Socialization Experiences II. Peer relationships (ppt)

Schaefer, D. R., Light, J. M., Fabes, R. A., Hanish, L. D., & Martin, C. L.. Fundamental principles of network formation among preschool children. Social Networks (2010). David5

Lynn Martin, C., Fabes, R. A., Hanish, L. D., & Hollenstein, T. (2005). Social dynamics in the preschool. Developmental Review, 25(3–4), 299-327. doi: http://dx.doi.org/10.1016/j.dr.2005.10.001.

Zosuls, K.M., Field, R.D.*, Martin, C.L., Andrews, N.C.Z.*, & England, D.E*. (2014). Gender-based relationship efficacy: Children’s self-perceptions in intergroup contexts. Child Development, 85, 1663-1676. DOI: 10.1111/cdev.12209

Extra:

Degnan, K. A., Almas, A. N., Henderson, H. A., Hane, A. A., Walker, O. L., & Fox, N. A. (2014). Longitudinal trajectories of social reticence with unfamiliar peers across early childhood. Developmental Psychology, 50(10), 2311-2323. doi: 10.1037/a0037751

Tuesday, November 8. (Election Day).

Socialization Experiences III. School and Community (ppt)

Vandell, D. L., Belsky, J., Burchinal, M., Steinberg, L., & Vandergrift, N. (2010). Do effects of early child care extend to age 15 years? Results from the NICHD study of early child care and youth development. Child Dev, 81(3), 737-756. doi: 10.1111/j.1467-8624.2010.01431.x Chelsea5

Thursday, November 10. Prematurity.

Mariette, M. M., & Buchanan, K. L. (2016). Prenatal acoustic communication programs offspring for high posthatching temperatures in a songbird. Science, 353(6301), 812-814. doi: 10.1126/science.aaf7049

Extra:

Harshaw, C., & Lickliter, R. (2011). Biased embryos: Prenatal experience and the malleability of species-typical auditory preferences. Developmental Psychobiology, 53, 291-302.

Sapparapu, G., Fernandez, E., Kose, N., Cao, B., Fox, J. M., Bombardi, R. G., Zhao, H., Nelson, C. A., Bryan, A. L., Barnes, T., Davidson, E., Mysorekar, I. U., Fremont, D. H., Doranz, B. J., Diamond, M. S., & Crowe, J. E. (2016). Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice. Nature, advance online publication. doi: 10.1038/nature20564.

Mlakar, J., Korva, M., Tul, N., Popović, M., Poljšak-Prijatelj, M., Mraz, J., Kolenc, M., Resman Rus, K., Vesnaver Vipotnik, T., Fabjan Vodušek, V., Vizjak, A., Pižem, J., Petrovec, M., & Avšič Županc, T. (2016). Zika Virus Associated with Microcephaly. New England Journal of Medicine, 374(10), 951-958. doi: doi:10.1056/NEJMoa1600651

Oliveira-Szejnfeld, P. S. d., Levine, D., Melo, A. S. d. O., Amorim, M. M. R., Batista, A. G. M., Chimelli, L., Tanuri, A., Aguiar, R. S., Malinger, G., Ximenes, R., Robertson, R., Szejnfeld, J., & Tovar-Moll, F. Congenital Brain Abnormalities and Zika Virus: What the Radiologist Can Expect to See Prenatally and Postnatally. Radiology, 0(0), 161584. doi: doi:10.1148/radiol.2016161584

Couzin, J. (2002). Quirks of Fetal Environment Felt Decades Later. Science, 296(5576), 2167-2169.

CRISPR, the disruptor

Embryo editing sparks epic debate

Tuesday, November 15. Students present draft PowerPoint presentations.

Extra:

Substance Exposure.

Lester, B. M., Bagner, D. M., Liu, J., LaGasse, L. L., Seifer, R., Bauer, C. R., Shankaran, S., et al. (2009). Infant neurobehavioral dysregulation: Behavior problems in children with prenatal substance exposure. Pediatrics, 124(5), 1355-1362.

Extra:

Rubin, E. J., Greene, M. F., & Baden, L. R. (2016). Zika Virus and Microcephaly. New England Journal of Medicine, 374(10), 984-985. doi: doi:10.1056/NEJMe1601862

Eze N, Smith LM, LaGasse LL, Derauf C, Newman E, Arria A, Huestis MA, DellaGrotta SA, Dansereau LM, Neal C, Lester BM. (2016) School-Aged outcomes following prenatal methamphetamine exposure: 7.5-year follow-up from the Infant Development, Environment, and Lifestyle Study. The Journal of Pediatrics. EPub ahead of print: doi:10.1016/j.peds.2015.11.070.

Stroud LR, Papandonatos GD, Salisbury AL, Phipps M, Huestis M, Niaura R, Marsit CJ, Lester BL. (2016) Epigenetic Regulation of Placental NR3C1: Mechanism underlying Prenatal Programming of Infant Neurobehavior by Maternal Smoking? Child Dev. Jan;87(1):49-60. doi: 10.1111/cdev.12482. PMID: 26822442 [PubMed - in process].

Thursday, November 17. No class.

Extra:

November 22 & 24. No class. Thanksgiving.

Tuesday, November 29. Joint attention

Gangi, D. N., Messinger, D. S., Martin, E. R., & Cuccaro, M. L. (2016). Dopaminergic variants in siblings at high risk for autism: Associations with initiating joint attention. Autism Research, n/a-n/a. doi: 10.1002/aur.1623

Thursday, December 1. Social development disrupted: Autism spectrum disorder [Blackboard].

Messinger, D., Young, G. S., Ozonoff, S., Dobkins, K., Carter, A., Zwaigenbaum, L., Landa, R. J., Charman, T., Stone, W. L., Constantino, J. N., Hutman, T., Carver, L. J., Bryson, S., Iverson, J. M., Strauss, M. S., Rogers, S. J., & Sigman, M. (2013). Beyond Autism: A Baby Sibling Research Consortium Study of High-Risk Children at Three Years of Age. Journal of the American Academy of Child and Adolescent Psychiatry, 52(3), 300-308. NIHMS 431543. PubMed 23452686

Understanding Delay in Developmental Disorders (pages 73–80)
Thomas, M. S. C. (2016). Understanding Delay in Developmental Disorders. Child Development Perspectives, 10(2), 73-80. doi: 10.1111/cdep.12169

Thomas, M. S. C., Davis, R., Karmiloff-Smith, A., Knowland, V. C. P., & Charman, T. (2015). The over-pruning hypothesis of autism. Developmental Science, n/a-n/a. doi: 10.1111/desc.12303.

Tuesday, December 6.

Student PowerPoint presentations.

Tuesday, 12/14. Final paper due.

Extra Material: